Related Experiment Video
Updated: May 18, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Chondroid chordoma and nasal adenocarcinoma: an exceptional association
Patrice Gallet1, Nathalie Marcon, Thomas Georgel
1Department of ENT and Cervico-Facial Surgery, University Hospital, University of Lorraine, 54003 Nancy Cedex, France.
Abstract:
Collision tumors are exceptional, associating two independent tumoral contingents. We report a case of an association of two rare tumors: sinonasal adenocarcinoma and chondroid chordoma. Initially, only adenocarcinoma was diagnosed. The treatment consisted of endoscopic endonasal surgery followed by conventional radiotherapy. After 18 months, a local recurrence was diagnosed after a facial trauma, but the true histology was difficult to assess. The tumor was dual, associating adenocarcinoma and chondroid chordoma, with atypical localization in the ethmoid. Further evolution was particularly aggressive. We discuss the key points of this observation.