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Related Concept Videos

Necrosis01:16

Necrosis

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Cellular Injury IV: Necrosis01:16

Cellular Injury IV: Necrosis

Necrosis is a form of irreversible cell death caused by severe injury such as ischemia, toxins, or trauma. Unlike programmed cell death, it is an uncontrolled, pathological process that typically provokes inflammation in surrounding tissues.Pathophysiologic ChangesNecrosis begins when cells sustain critical damage, leading to swelling of organelles, particularly mitochondria, and rapid ATP depletion. As energy levels decline, membrane ion pumps fail, leading to calcium influx and eventually,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

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Related Experiment Videos

Necrotizing fasciitis: an unusual presentation.

Vivek Sasindran1, Antony Joseph

  • 1Pushpagiri Institute of Medical Sciences, Thiruvalla, Kerala.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|October 2, 2012
PubMed
Summary

Necrotizing fasciitis (NF) is a rare, severe soft tissue infection. This case highlights acute cervical necrotizing fasciitis in a young male, emphasizing early diagnosis for better outcomes.

Keywords:
Diabetes mellitusNecrotizing fasciitisSoft tissue infections

Related Experiment Videos

Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Emergency Medicine

Background:

  • Necrotizing fasciitis (NF) is a severe, rapidly progressing soft tissue infection.
  • It typically affects the groin, abdomen, and extremities.
  • Head and neck NF is rare but associated with high morbidity and mortality.

Observation:

  • This report details a case of acute onset cervical necrotizing fasciitis.
  • The patient was a young male presenting with this rare condition.
  • The infection rapidly affected the subcutaneous tissues and fascial planes of the neck.

Findings:

  • The case illustrates the challenges in diagnosing NF in the head and neck.
  • Prompt recognition and intervention are crucial for patient survival.
  • Aggressive management is imperative for successful outcomes in cervical NF.

Implications:

  • Early diagnosis and treatment of head and neck NF are critical.
  • Increased awareness among clinicians can improve patient outcomes.
  • This case underscores the need for vigilance in identifying rare NF presentations.