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[Bacteroides fragilis septicemia].

J L Blache, F Gouin, Y Peloux

    Annales De L'Anesthesiologie Francaise
    |January 1, 1977
    PubMed
    Summary
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    Bacteroides fragilis septicaemia is increasingly common, often originating from surgical sites or postpartum conditions. Metronidazole and tinidazole are effective treatments, with potential for preventive use in high-risk patients.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Clinical Medicine

    Context:

    • Bacteroides fragilis is an increasingly prevalent cause of septicaemia.
    • Common entry points include localized suppuration post-surgery (digestive, gynecological) and postpartum/post-abortion periods.
    • Septicemia cases attributed to B. fragilis are rising, now representing approximately 10% of all septicemias.

    Purpose:

    • To review recent literature on Bacteroides fragilis septicaemia.
    • To highlight the increasing prevalence and common sources of infection.
    • To discuss current therapeutic strategies and their efficacy.

    Summary:

    • The study reviews eight cases of Bacteroides fragilis septicaemia and relevant literature.
    • Identifies digestive/gynecological surgery and postpartum periods as frequent infection origins.

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  • Emphasizes imidazole derivatives (metronidazole, tinidazole) as highly effective treatments.
  • Impact:

    • Informs clinicians about the rising incidence of B. fragilis septicaemia.
    • Guides therapeutic choices towards imidazole derivatives for effective treatment.
    • Suggests potential for prophylactic use of antibiotics in high-risk individuals.