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Updated: May 18, 2026
Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound
Published on: May 8, 2012
Effects of low-intensity pulsed ultrasound on autogenous bone graft healing
Yavuz Fındık1, Timuçin Baykul2
1Research Assistant Doctor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Süleyman Demirel University, Isparta, Turkey.
Objective:
Pulsed ultrasonic waves have been shown to accelerate bone healing. The aim of this study was to evaluate the effects of low-intensity pulsed ultrasound on bone healing.
Study Design:
Thirty-two femurs from 16 skeletally mature male Wistar albino rats were used. Two defects were produced in each femur with a 3-mm-diameter trephine bur and then autogenous cortical grafts were placed in 1 defect. The animals in the experiment group received a daily 20-minute ultrasound treatment for 15 days. All animals were killed on the 18th postoperative day.
Results:
Dual-energy x-ray absorptiometry values and biochemical markers in the experimental side were significantly higher than those in the control side at the early period of bone healing.
Conclusions:
Low-intensity pulsed ultrasound treatment accelerates bone healing both in bone defects and in bone defects filled with cortical autogenous block graft.
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