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Related Experiment Videos

Translocation (1;6)(p12;p23) in ANLL.

A K Jacob1, C Sreekantaiah, M R Baer

  • 1Cancer Center, Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.

Cancer Genetics and Cytogenetics
|March 1, 1990
PubMed
Summary

This case study details acute nonlymphocytic leukemia developing from myelodysplastic syndrome in an elderly patient. A novel chromosomal translocation, t(1;6)(p13;p23), involving oncogenes was identified in this hematologic malignancy.

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Cytogenetic and FISH studies of abnormal X chromosomes in a patient with ANLL.

Cancer genetics and cytogenetics·1992

Area of Science:

  • Hematology
  • Oncology
  • Cytogenetics

Background:

  • Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders.
  • Acute nonlymphocytic leukemia (ANLL) can evolve from MDS.
  • Prior radiation therapy is a risk factor for secondary malignancies.