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Varicocele repair for low testosterone.

Harry Fisch¹, Grace Hyun

¹Weill Cornell Medical College/New York Presbyterian Hospital, New York, New York 10028, USA. HarryFisch@aol.com

Current Opinion in Urology

|October 3, 2012

Summary

This summary is machine-generated.

Varicocele repair effectively increases testosterone levels in hypogonadal men. Recent studies confirm that varicocelectomy reliably restores testosterone to normal ranges in patients with low levels.

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Area of Science:

Andrology
Urology
Endocrinology

Background:

Varicocele is a common cause of male infertility.
Hypogonadism is associated with low serum testosterone levels.
The impact of varicocele repair on testosterone is a subject of ongoing research.

Purpose of the Study:

To review recent clinical studies on the effect of varicocelectomy on serum testosterone.
To evaluate the evidence supporting varicocele repair for restoring testosterone levels.

Main Methods:

Systematic review of recent clinical studies.
Analysis of studies published in 2011 regarding varicocele repair and testosterone.
Assessment of study power to detect testosterone changes.

Main Results:

Three adequately powered studies published in 2011 demonstrated significant increases in testosterone levels post-varicocelectomy.
These increases were observed in patients with pre-procedure low testosterone levels.
Varicocele repair showed a positive impact on restoring testosterone.

Conclusions:

Varicocele repair is an effective treatment for hypogonadal patients with varicoceles.
Surgical correction of varicocele can restore testosterone to eugonadal levels.
Evidence supports varicocelectomy for both unilateral and bilateral varicoceles in hypogonadal men.