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Measuring the elastic properties of living cells with atomic force microscopy indentation

Joanna L Mackay1, Sanjay Kumar

  • 1Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|October 3, 2012
PubMed

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Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...