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Updated: May 18, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Managing risk of complications at femoral vascular access sites in percutaneous coronary intervention
Nakia Merriweather1, Linda M Sulzbach-Hoke
1Echocardiography Laboratory, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Insights
Potent antiplatelet and antithrombin medications used in percutaneous coronary intervention increase vascular access complication risks. Nurses knowledgeable in risk factors can identify and mitigate these complications, improving patient outcomes.
Area of Science:
- Cardiology
- Vascular Medicine
- Nursing
Background:
- Percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) or non-ST-elevation myocardial infarction (NSTEMI) necessitates potent antiplatelet and antithrombin therapies.
- While enhancing PCI efficacy, these potent antithrombotic agents elevate the risk of vascular access complications.
Purpose of the Study:
- To review the risks associated with potent antithrombotic agents used in PCI.
- To identify modifiable and nonmodifiable risk factors for vascular access complications.
- To emphasize the role of nurses in mitigating these complications.
Main Methods:
- Literature review of studies on PCI, antithrombotic agents, and vascular access complications.
- Analysis of risk factors, including procedural techniques, medications, hemostasis, patient demographics, and physiological parameters.
- Discussion of nursing interventions for complication identification and management.
Main Results:
- Vascular access complications include hematoma, retroperitoneal hematoma, pseudoaneurysm, arterial occlusion, and arteriovenous fistula.
- Complications are linked to increased morbidity, mortality, and healthcare costs.
- Risk factors are categorized as modifiable (e.g., procedure technique, medications) and nonmodifiable (e.g., age, sex, BMI, renal function).
Conclusions:
- Nurses play a critical role in recognizing and managing vascular access complications post-PCI.
- Knowledge of risk factors empowers nurses to implement preventative strategies and early interventions.
- Effective nursing care can reduce the incidence and severity of complications, improving patient safety and outcomes.
Abstract:
Percutaneous coronary intervention for acute coronary syndrome or non-ST-elevation myocardial infarction requires the use of potent oral and intravenous anti-platelet and antithrombin medications. Although these potent antithrombotic agents and regimens may increase the effectiveness of percutaneous coronary intervention, they are also generally associated with an increased risk of vascular access complications such as hematoma, retroperitoneal hematoma, pseudoaneurysm, arterial occlusion, and arteriovenous fistula, which in turn are associated with increased morbidity, mortality, and costs. Risk factors predisposing patients to these complications are both modifiable (procedure technique, medications, hemostasis method) and nonmodifiable (sex, age, body mass index, blood pressure, renal function). Patients' risks can be reduced by nurses who are knowledgeable about these risk factors and identify complications before they become problematic.
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