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Related Experiment Video

Updated: May 18, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Age-related changes in task related functional network connectivity.

Jason Steffener¹, Christian G Habeck, Yaakov Stern

¹Cognitive Neuroscience Division, Department of Neurology and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, United States of America. js2746@columbia.edu

|October 3, 2012

Summary

This summary is machine-generated.

Aging affects brain connectivity, impacting cognitive performance. Older adults showed reduced functional network connectivity, linked to slower task speeds, but not global brain volume changes.

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Published on: March 21, 2019

Area of Science:

Neuroscience
Cognitive Aging Research

Background:

Aging impacts brain structure, function, and cognition.
The interplay between these age-related changes is not well understood.

Purpose of the Study:

To investigate how age-related structural changes affect brain functional connectivity.
To determine the impact of altered connectivity on cognitive task performance in aging.

Main Methods:

Used independent components analysis (ICA) for neuroimaging.
Analyzed functional connectivity during a verbal delayed item recognition task.
Compared 75 healthy young adults and 37 healthy old adults.

Main Results:

Functional network connectivity differed between young and old adults during the task.
Reduced connectivity in older adults correlated with slower task performance.
Age-related connectivity changes were independent of global brain volume differences.

Conclusions:

Age-related differences in neural coordination contribute to cognitive performance variations.
Functional network connectivity alterations are a key factor in cognitive aging.