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Updated: May 18, 2026
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Dengue fever with unusual thalamic involvement
Asim Kumar Mallick1, Radheshyam Purkait, Tapan Kumar Sinhamahapatra
1Department of Paediatric Medicine, NRS Medical College and Hospital, Kolkata 700014.
Journal of the Indian Medical Association
|October 4, 2012
Summary
Dengue virus infection can cause serious neurological complications. This case highlights rare thalamic involvement leading to hemiplegia, emphasizing the evolving clinical presentation of dengue.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Dengue virus is a major global mosquito-borne illness, with four serotypes.
- Infections range from asymptomatic to severe dengue hemorrhagic fever.
- Neurological complications of dengue are increasingly recognized.
Observation:
- Neurological manifestations of dengue include headache, seizures, and paralysis.
- Cerebral edema, encephalitis-like changes, and intracranial hemorrhages have been noted.
- Thalamic involvement in dengue infection is exceptionally rare.
Findings:
- This report details a case of dengue-associated encephalopathy.
- The patient presented with left-sided complete hemiplegia.
- Neuroimaging revealed specific thalamic involvement as the cause.
Implications:
- The findings suggest dengue can affect the central nervous system in unusual ways.
- This case expands the spectrum of known dengue neurological complications.
- Increased awareness of rare neurological presentations is crucial for timely diagnosis and management of dengue.
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