Related Experiment Video
Updated: May 18, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Exogenous surfactant replacement: how to deliver it?
Paolo Biban1, Lorenza Chini, Paolo Bonetti
1Neonatal and Paediatric Intensive Care Unit, Department of Paediatrics, Major City Hospital, Azienda Ospedaliera Universitaria Integrata, Verona, Italy. paolo.biban@ospedaleuniverona.it
Abstract:
Exogenous surfactant is a therapeutic option for newborns, children and adults with acute respiratory distress disorders. Although tracheal instillation is still reputed as the classical method of surfactant delivery, alternative techniques have been investigated. Surfactant administration by using thin intra-tracheal catheters, bronchoscopy, laryngeal mask airway, or nebulisation, although variably effective, appear to be less invasive when compared to tracheal intubation. However, further research is still needed to better clarify this matter. (www.actabiomedica.it).
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