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Updated: Aug 19, 2026
11:20
Quantitative Assessment of Human Neutrophil Migration Across a Cultured Bladder Epithelium
Published on: November 7, 2013
Effect of fusidic acid on migration and chemiluminescence of polymorphonuclear leukocytes
A Naess1, R W Flø, C O Solberg
1Medical Department B, Haukeland Hospital, University of Bergen, Norway.
Abstract:
Incubation of polymorphonuclear leukocytes (PMNs) in fusidic acid resulted in a decrease of random migration and chemiluminescence. The effects were dose-dependent but moderate, with statistical significance only at concentrations of 50 mg/l or more. At concentrations used for therapy of bacterial infections and AIDS, fusidic acid was not shown to be deleterious to these aspects of PMN function.
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