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Updated: May 18, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

[Splenic marginal zone lymphoma]

Konstantinos Dimopoulos1, Michael Pedersen

  • 1Hæmatologisk Afdeling, Herlev Hospital, Herlev Ringvej 75, Herlev. stamatiskostas@msn.com

Ugeskrift for Laeger
|October 4, 2012
PubMed

Splenic marginal zone lymphoma (SMZL) with or without villous lymphocytes is a low-grade malignant lymphoma, which primarily involves the spleen, the bone marrow and the blood. Even though the prognosis of the disease is good and there is a long overall survival, about two thirds of the patients will require treatment and in 10% of the patients the lymphoma will transform into a high-grade malignant lymphoma. The treatment of SMZL remains empirical, since there is lack of large, prospective studies. Without such studies, the best treatment modality cannot be established.

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