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Infrared (IR) Spectroscopy: Overview

Infrared (IR) Spectroscopy: Overview

When electromagnetic radiation passes through a material, atoms or molecules transition from a lower to a higher energy state by absorbing radiation corresponding to the energy difference between the two states. The absorption of infrared (IR) radiation causes transitions between vibrational energy levels in a molecule. Therefore, IR spectroscopy is a useful analytical tool for determining the molecular structure of molecules.
Different compounds display unique properties due to their...

Applications of IR Spectroscopy: Overview

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The non-destructive nature and ability to provide valuable chemical information make IR spectroscopy a versatile technique with broad applications in various scientific and industrial fields. IR spectroscopy is commonly used to identify and characterize organic and inorganic compounds. It provides information about the functional groups present in a molecule and the bonding between atoms. This helps in the structural elucidation of compounds during organic synthesis, pharmaceutical research,...

IR Spectrometers

IR Spectrometers

There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...

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High-definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology

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Published on: January 21, 2015

Infrared spectroscopic imaging: the next generation.

Rohit Bhargava¹

¹Department of Bioengineering, Beckman Institute for Advanced Science and Technology, University of Illinois Cancer Center, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. rxb@illinois.edu

Applied Spectroscopy

|October 4, 2012

Summary

Recent advances in infrared (IR) spectroscopic imaging have transformed data interpretation and information extraction. New trends focus on application-specific instrumentation and advanced signal processing for enhanced scientific insight.

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Area of Science:

Spectroscopy
Optical Physics
Chemical Analysis

Background:

Infrared (IR) spectroscopic imaging matured in the mid-2000s with commercial instrumentation.
Recent developments have significantly advanced data understanding and information extraction capabilities.

Purpose of the Study:

To review recent developments in IR spectroscopic imaging.
To project emerging trends in instrumentation, data interpretation, and information extraction.

Main Methods:

Critical review of advancements in data recording, interpretation, and information extraction.
Analysis of hardware, theory, algorithms, and application convergence.
Projection of future trends in IR spectroscopic imaging.

Main Results:

Emerging trends include component convergence and diverse, application-targeted instrumentation.
Improved data interpretation at the intersection of spectroscopy and optical physics.
Shift towards signal processing algorithms for optimal spectral and spatial information extraction before chemometrics.

Conclusions:

Recent advances offer unprecedented measurement capabilities and scientific insight.
New opportunities are emerging for applied spectroscopists.
The field is poised for significant innovation driven by fundamental science and instrumentation.