Resolution of relapsing thrombus by heparin therapy in right ventricular dysplasia

A 22-year-old-patient presented with ventricular tachycardia and echocardiographic signs of right ventricular dysplasia. Fifteen months later, the echocardiogram disclosed a huge right ventricular thrombus. Heparin therapy resulted in resolution of the thrombus. Despite chronic anticoagulation, the thrombus reappeared 9 months later, again resolving after heparin therapy. To our knowledge, right ventricular thrombosis in the setting of right ventricular dysplasia has not been previously described and might explain some cases of sudden death in this entity.