Related Experiment Videos
Oxygen permeability of collagen shields
B A Weissman1, N A Brennan, D A Lee
1Jules Stein Eye Institute, Department of Ophthalmology, University of California, Los Angeles School of Medicine 90024-1771.
Investigative Ophthalmology & Visual Science
|February 1, 1990
Summary
Collagen shields demonstrate adequate oxygen permeability (Dk) for corneal health. Their measured Dk is compatible with normal corneal metabolism, ensuring sufficient oxygen supply.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- Collagen shields are used in ophthalmic applications.
- Understanding their oxygen permeability is crucial for corneal health.
Purpose of the Study:
- To measure the oxygen permeability (Dk) of 24-hour collagen shields.
- To assess the compatibility of collagen shields with corneal metabolism.
Main Methods:
- Oxygen permeability (Dk) measured using polarographic methodology.
- Measurements taken at approximately 2 hours of hydration.
- Edge and boundary effects were incorporated into calculations.
Main Results:
- The oxygen permeability (Dk) was found to be approximately 26 x 10(-11) cm ml O2/sec ml mmHg at 35°C.
- Mean water content of the shields was 65.7% (SD = 1.0%).
Conclusions:
- The measured oxygen permeability of collagen shields is projected to be compatible with normal corneal metabolism.
- Collagen shields offer sufficient oxygen transmissibility for ocular surface health.