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Published on: October 25, 2013
Nanomechanical identification of proteins using microcantilever-based chemical sensors
1Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Nanoscale
|October 5, 2012
Abstract:
We have developed a microcantilever based sensor array which can be functionalized with mercapto-compounds to detect proteins. Linear discriminant analysis (LDA) is used to differentiate the cantilever deflection patterns. It is concluded that more sensors give better separating capacity and the COOH and Si-OCH(3) groups are important factors in protein recognition.

