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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Published on: March 24, 2020

Widely separated composite split cord malformation.

Deepak Kumar Singh¹, Neha Singh, Ragini Singh

¹Department of Neurosurgery, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.

BMJ Case Reports

|October 5, 2012

Summary

This summary is machine-generated.

This report details a rare case of split cord malformations (SCMs) in an 18-month-old child affecting two distinct spinal regions. Such widely separated SCMs are infrequently documented in medical literature.

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Area of Science:

Pediatric Neurology
Developmental Biology
Spinal Cord Anomalies

Background:

Split cord malformation (SCM) is a rare congenital anomaly involving the division of the spinal cord.
SCMs typically occur as a single event, with varying locations along the spinal axis.
Understanding the embryological basis of SCM is crucial for diagnosing and managing these complex conditions.

Observation:

An 18-month-old child presented with split cord malformations (SCMs).
The SCMs were identified at two distinct and widely separated levels: the upper thoracic (T2) and lumbar (L2) regions.
This dual-level occurrence represents a rare anatomical variation.

Findings:

The case highlights the possibility of split cord malformations occurring at multiple, distant spinal cord levels.
Radiological and clinical findings confirmed the presence of SCMs at both T2 and L2.
The rarity of this specific presentation (wide separation) is emphasized, with few similar cases reported.

Implications:

This case expands the known spectrum of split cord malformation presentations.
It underscores the importance of thorough spinal imaging in pediatric patients with suspected congenital anomalies.
Further research into the developmental mechanisms underlying multiple SCMs may be warranted.