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MIC1-MAG1-SAG1 chimeric protein, a most effective antigen for detection of human toxoplasmosis

Lucyna Holec-Gasior1, Bartlomiej Ferra, Dorota Drapala

  • 1Gdańsk University of Technology, Chemical Faculty, Department of Microbiology, Gdańsk, Poland. holec@pg.gda.pl

Clinical and Vaccine Immunology : CVI
|October 5, 2012
PubMed

This study describes a Toxoplasma gondii IgG enzyme-linked immunosorbent assay based on a new chimeric antigen containing three immunodominant regions from the MIC1, MAG1, and SAG1 proteins of the parasite and shows that this test is useful for diagnostic purposes and may replace the lysed and whole-cell antigens.

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