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Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
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Suctioning the Nasopharyngeal Airway

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Related Experiment Video

Updated: May 18, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

Using negative pressure therapy in wound healing.

Heidi Guy1, Lorraine Grothier

  • 1East and North Herts Hospital Trust.

Nursing Times
|October 6, 2012
PubMed
Summary

Negative pressure wound therapy (NPWT) is an effective treatment for acute and chronic wounds, supported by strong evidence. This therapy is applicable in both primary and acute care settings.

Area of Science:

  • Wound healing
  • Medical technology
  • Clinical practice

Background:

  • Negative pressure wound therapy (NPWT), also known as topical negative pressure therapy, is increasingly utilized in wound management.
  • It offers a distinct approach compared to traditional wound treatments and dressings.
  • A notable feature of NPWT is its robust evidence base supporting its efficacy.

Purpose of the Study:

  • To review the applications of negative pressure wound therapy.
  • To discuss the evidence supporting NPWT effectiveness.
  • To explore NPWT's role in primary and acute care settings.

Main Methods:

  • Literature review of studies on negative pressure wound therapy.
  • Analysis of evidence supporting NPWT efficacy.

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Related Experiment Videos

Last Updated: May 18, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
09:41

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications

Published on: May 10, 2024

  • Discussion of clinical applications in different care settings.

    • Main Results:

    • Negative pressure wound therapy demonstrates significant effectiveness across various wound types.
    • The evidence base for NPWT is more substantial than for many alternative treatments.
    • NPWT is a viable and beneficial option for both primary and acute wound care.

    Conclusions:

    • Negative pressure wound therapy is a well-supported and effective treatment modality.
    • Its application spans both primary and acute care, offering versatility.
    • Clinicians should consider NPWT for managing a range of acute and chronic wounds.