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Predicting feasibility and characterizing performance of extended-release formulations using physiologically based

Jonathan Brown1, John Crison, Peter Timmins

  • 1Drug Product Science & Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Merseyside CH46 IQW, UK.

Therapeutic Delivery
|October 6, 2012
PubMed
Summary

Physiologically based pharmacokinetic modeling aids extended-release (ER) formulation development by optimizing drug release rates for improved clinical performance. This in silico approach is increasingly vital for efficient drug product design and quality by design.

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