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Pretibial epidermolysis bullosa: report of a case
D J Lichtenwald1, W Hanna, D N Sauder
1Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Journal of the American Academy of Dermatology
|February 1, 1990
Abstract:
Pretibial epidermolysis bullosa is a rare variant of hereditary epidermolysis bullosa that is characterized by the delayed onset of a blistering eruption limited to the pretibial area. We present a case in a 48-year-old woman. Immunofluorescence mapping demonstrated blister formation below the basement membrane. This was confirmed by ultrastructural investigations that also revealed rudimentary anchoring fibrils similar to those described in the dominant dystrophic forms of epidermolysis bullosa.