Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rab Cascades01:25

Rab Cascades

Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hyper-dimensional computing for enhanced label-free particle analysis in a flow-based optical detection system.

Scientific reports·2026
Same author

Reshaping reservoirs with unsupervised Hebbian adaptation.

Nature communications·2025
Same author

Optical signal acquisition using an alignment robust receiver based on a photodetector array.

Optics letters·2025
Same author

Enhanced feedback sensitivity suppression in phase-detuned tunable lasers with high-Q Vernier-effect based ring resonators.

Optics express·2025
Same author

Advanced characterization and parameter extraction of electrically injected InGaAs/GaAs nano-ridge lasers monolithically integrated on silicon.

Optics express·2025
Same author

Shapley-guided global optimization algorithm with applications in integrated photonics inverse design.

Optics express·2025

Related Experiment Video

Updated: May 18, 2026

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction
07:01

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction

Published on: September 25, 2017

Cascadable excitability in microrings.

Thomas Van Vaerenbergh1, Martin Fiers, Pauline Mechet

  • 1Photonics Research Group (INTEC), Ghent University - imec, Sint-Pietersnieuwstraat 41, B-9000 Ghent, Belgium. thomas.vanvaerenbergh@intec.ugent.be

Optics Express
|October 6, 2012
PubMed
Summary
This summary is machine-generated.

This study demonstrates cascadable excitability in silicon microrings, a key feature for photonic spiking neurons. The research shows class II excitability, paving the way for advanced optical computing components.

More Related Videos

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
08:44

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism

Published on: October 17, 2025

Related Experiment Videos

Last Updated: May 18, 2026

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction
07:01

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction

Published on: September 25, 2017

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
08:44

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism

Published on: October 17, 2025

Area of Science:

  • Photonics
  • Nonlinear Optics
  • Biophysics

Background:

  • Spiking neurons are fundamental to biological computation.
  • Photonic components offer potential for high-speed, low-power neuromorphic computing.
  • Achieving excitability in photonic systems is crucial for emulating neuron-like behavior.

Purpose of the Study:

  • To theoretically simulate and experimentally demonstrate cascadable excitability in high-Q-factor silicon-on-insulator microrings.
  • To investigate the underlying nonlinear dynamics leading to excitability.
  • To confirm the suitability of this mechanism for scalable photonic neural networks.

Main Methods:

  • Coupled Mode Theory for theoretical simulation.
  • Analysis of microring dynamics using temperature and free carriers as variables.
  • 2D phase portrait analysis to identify bifurcations.
  • Experimental characterization of single microring excitability and self-pulsation.

Main Results:

  • Demonstration of subcritical Andronov-Hopf bifurcation at the self-pulsation onset.
  • Observation of class II excitability in the microring system.
  • Experimental validation of theoretical predictions for excitability and self-pulsation.
  • Confirmation of the cascadable nature of the excitation mechanism.

Conclusions:

  • High-Q-factor silicon microrings exhibit class II excitability, essential for spiking neuron emulation.
  • The demonstrated cascadable excitation mechanism is suitable for building scalable photonic neural systems.
  • This work provides a pathway towards efficient and compact optical neuromorphic hardware.