Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic molecular and cytogenetic screening of 100 patients with marfanoid syndromes and intellectual disability.

Clinical genetics·2013
Same author

[A lung cavity with an air crescent].

Revue des maladies respiratoires·2012
Same author

[Tobacco and marijuana use in adolescent students in Noumea].

Revue des maladies respiratoires·2011
Same author

Invasive serotype 1 Streptococcus pneumoniae outbreaks in the South Pacific from 2000 to 2007.

Journal of clinical microbiology·2010
Same author

[Pancreatic-portal fistula after acute pancreatitis].

Gastroenterologie clinique et biologique·2008
Same author

[Laryngeal schwannoma: a case report and review of the literature].

Revue de laryngologie - otologie - rhinologie·2007

Related Experiment Video

Updated: May 18, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

[Leprosy with an unusual course].

A Desenfants1, E Huguon, Y Polfrit

  • 1Service de pédiatrie, hôpital Magenta, centre hospitalier territorial de Nouvelle-Calédonie, BP J5, 98849 Nouméa cedex, France. auredsf@hotmail.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|October 6, 2012
PubMed
Summary
This summary is machine-generated.

Hansen disease (leprosy) is rare in developed nations. This case highlights an unusual lepromatous leprosy reaction in an 11-year-old, presenting complex symptoms and requiring careful management for a positive outcome.

More Related Videos

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)

Published on: July 15, 2011

Related Experiment Videos

Last Updated: May 18, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)

Published on: July 15, 2011

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pediatrics

Context:

  • Hansen disease (leprosy) is rare in developed countries, with stable prevalence in New Caledonia.
  • Leprosy can present with complex complications, even with appropriate treatment.
  • Type 2 reactions in leprosy can mimic other systemic illnesses.

Purpose:

  • To report a rare case of lepromatous leprosy with a complicated type 2 reaction in a child.
  • To discuss the differential diagnoses and potential causes of unusual clinical and biological manifestations.
  • To describe the successful therapeutic management of this complex case.

Summary:

  • An 11-year-old presented with lepromatous leprosy and a type 2 reaction, exhibiting prolonged fever, asthenia, weight loss, and laboratory abnormalities.
  • Investigated causes included dapsone-induced hemolytic anemia, the type 2 reaction itself, and features of hemophagocytic syndrome.
  • Multifaceted therapeutic strategies were employed, leading to a favorable clinical outcome.

Impact:

  • This case underscores the importance of considering leprosy and its reactions in pediatric patients, even in low-prevalence areas.
  • It highlights the diagnostic challenges posed by atypical presentations of leprosy complications.
  • Provides insights into managing complex leprosy cases with systemic involvement.