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Published on: June 20, 2020
Functional outcome of very preterm-born and small-for-gestational-age children at school age
Jozien C Tanis1, Meike H van der Ree, Elise Roze
1Division of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. j.c.tanis@umcg.nl
Insights
Very preterm-born children who were small-for-gestational-age (SGA) showed slight deficits in motor skills and attention compared to controls. These functional outcomes appear linked to preterm birth itself, not SGA status.
Area of Science:
- Neonatal development
- Pediatric neurology
- Developmental psychology
Background:
- Preterm birth and small-for-gestational-age (SGA) are associated with potential developmental challenges.
- Understanding the specific functional outcomes in these children is crucial for early intervention.
Purpose of the Study:
- To compare the school-age functional outcomes of very preterm-born SGA children with matched controls.
- To determine if developmental differences are primarily due to preterm birth or SGA status.
Main Methods:
- A cohort of 28 very preterm SGA children (gestational age <32 weeks) was compared to 28 matched very preterm appropriate-for-gestational-age (AGA) controls.
- Assessments included motor skills, IQ, attention, memory, visual perception, executive functioning, and behavior at school age.
Main Results:
- SGA children exhibited significantly lower Performance IQ, total motor skills, fine motor skills, selective attention, and visual perception compared to controls.
- No significant differences were found in total IQ or verbal IQ between the groups.
Conclusions:
- The observed functional differences between very preterm SGA children and controls were small.
- Findings suggest that the impaired functioning is more attributable to the effects of very preterm birth than to being SGA.
Background:
Our aim was to determine functional outcome of very preterm-born and small-for-gestational-age (SGA) children as compared with matched controls at school age.
Methods:
We included 28 very preterm SGA children (GA <32 wk, birth weight (BW) <10th percentile), born in 2000-2001. We also included 28 very preterm but appropriate-for-gestational-age (AGA) children, matched for GA, gender, and birth year, as controls. We assessed motor skills, intelligence quotient (IQ), attention, verbal memory, visual perception, visuomotor integration, executive functioning, and behavior of both sets of children at school age.
Results:
The SGA children had a median GA of 29.7 wk and BW of 888 g, whereas the controls had a median GA of 29.4 wk and BW of 1,163 g. At 8.6 y, the median total IQ of the SGA children was 94 as compared with 95 in the controls (not significant). Performance IQ was significantly lower in SGA children (89 vs. 95, P = 0.043), whereas verbal IQ was not (95 vs. 95). Total motor skills (P = 0.048) and fine motor skills (P = 0.021) were worse in SGA children. Furthermore, SGA children scored lower on selective attention (P = 0.026) and visual perception (P = 0.025). Other scores did not differ significantly between groups.
Conclusion:
The differences we found between the groups were small. This suggests that the impaired functioning of very preterm-born SGA children is attributable to their having been born very preterm rather than to being SGA.
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