Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Metal-Semiconductor Junctions

Metal-Semiconductor Junctions

The contact of metal and semiconductor can lead to the formation of a junction with either Schottky or Ohmic behavior.
Schottky Barriers
Schottky barriers arise when a metal with a work function (Φm) contacts a semiconductor with a different work function (Φs). Initially, electrons transfer until the Fermi levels of the metal and semiconductor align at equilibrium. For instance, if Φm > Φs, the semiconductor Fermi level is higher than the metal's before contact. The semiconductor's...

Potentiometry: Membrane Electrodes

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Smooth constrained block matching algorithm for the evaluation of diaphragm deformation in speckle-tracking ultrasound.

Frontiers in medicine·2026

Same author

Berberine alleviates hypersensitivity pneumonitis-like lung inflammation by restoring TFEB-dependent autophagic flux and neutrophil homeostasis.

Cellular signalling·2026

Same author

Theoretical investigation of momentum-dependent carrier-carrier scattering from crystal-strong laser interaction.

Optics express·2026

Same author

Dapagliflozin May Attenuate Podocyte Injury in Diabetic Kidney Disease through Inhibition of Lactate-Mediated H4K12 Lactylation.

Kidney & blood pressure research·2026

Same author

DNA Methylation Regulates CDK5R1 and NRBP1 to Exert Effects on Alcohol Dependence: Insights From Mendelian Randomization.

Addiction biology·2026

Same author

Identification of oviposition attractants for Peridroma saucia based on characterization of the female antennal-predominant odorant-binding protein PsauOBP6.

Pest management science·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

Monitoring Protein Adsorption with Solid-state Nanopores

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

Palladium electrodes for molecular tunnel junctions.

Shuai Chang¹, Suman Sen, Peiming Zhang

¹Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

|October 6, 2012

Summary

This summary is machine-generated.

Palladium electrodes offer cleaner signals for molecular tunneling junctions compared to gold. This advancement enables accurate recognition of DNA bases in electronic devices.

More Related Videos

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Published on: January 8, 2016

Related Experiment Videos

Last Updated: May 18, 2026

Monitoring Protein Adsorption with Solid-state Nanopores

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Published on: January 8, 2016

Area of Science:

Nanotechnology
Molecular Electronics
Biophysics

Background:

Gold is traditionally used for molecular tunneling junctions but is incompatible with semiconductor fabrication.
Gold contamination in silicon creates deep level traps, hindering device performance.
Alternative electrode materials are needed for reliable molecular electronic devices.

Purpose of the Study:

To investigate palladium as an alternative electrode material for molecular tunneling junctions.
To develop a recognition-tunneling junction for accurate DNA base detection.
To improve signal clarity and reduce background noise in molecular electronic devices.

Main Methods:

Fabrication of molecular tunneling junctions using palladium electrodes.
Testing the recognition capabilities of the junctions with natural DNA bases and 5-methyl cytosine.
Analysis of tunnel current signals to assess base identification accuracy.

Main Results:

Palladium electrodes do not contaminate silicon, unlike gold.
Higher tunnel current signals were observed with palladium electrodes.
A recognition-tunneling junction demonstrated accurate identification of four natural DNA bases and 5-methyl cytosine.
Over 75% of signal peaks correctly identified the DNA base, with no spurious background signals.

Conclusions:

Palladium is a superior electrode material for molecular tunneling junctions, offering improved signal quality and semiconductor compatibility.
The developed recognition-tunneling junction shows high accuracy in identifying DNA bases, paving the way for advanced biosensors.
This work overcomes limitations of gold electrodes, enabling cleaner and more reliable molecular electronic devices.