Related Experiment Video
Updated: May 18, 2026
Mapping Molecular Diffusion in the Plasma Membrane by Multiple-Target Tracing (MTT)
Published on: May 27, 2012
MITK diffusion imaging
K H Fritzsche1, P F Neher, I Reicht
1German Cancer Research Centre, E 130 - Division of Medical and Biological Informatics, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. k.fritzsche@dkfz-heidelberg.de
Background:
Diffusion-MRI provides a unique window on brain anatomy and insights into aspects of tissue structure in living humans that could not be studied previously. There is a major effort in this rapidly evolving field of research to develop the algorithmic tools necessary to cope with the complexity of the datasets.
Objectives:
This work illustrates our strategy that encompasses the development of a modularized and open software tool for data processing, visualization and interactive exploration in diffusion imaging research and aims at reinforcing sustainable evaluation and progress in the field.
Methods:
In this paper, the usability and capabilities of a new application and toolkit component of the Medical Imaging and Interaction Toolkit (MITK, www.mitk.org), MITK-DI, are demonstrated using in-vivo datasets.
Results:
MITK-DI provides a comprehensive software framework for high-performance data processing, analysis and interactive data exploration, which is designed in a modular, extensible fashion (using CTK) and in adherence to widely accepted coding standards (e.g. ITK, VTK). MITK-DI is available both as an open source software development toolkit and as a ready-to-use installable application.
Conclusions:
The open source release of the modular MITK-DI tools will increase verifiability and comparability within the research community and will also be an important step towards bringing many of the current techniques towards clinical application.
