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Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

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Related Experiment Video

Updated: May 18, 2026

Generation and Maintenance of Primate Induced Pluripotent Stem Cells Derived from Urine
07:46

Generation and Maintenance of Primate Induced Pluripotent Stem Cells Derived from Urine

Published on: July 28, 2023

Urine as a source of stem cells.

Christina Benda1, Ting Zhou, Xianming Wang

  • 1Key Laboratory of Regenerative Biology, Chinese Academy of Sciences, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Guangzhou, 510530, China, christina@gibh.ac.cn.

Advances in Biochemical Engineering/Biotechnology
|October 6, 2012
PubMed
Summary

Urine offers a noninvasive source for cell expansion and biological studies, challenging the traditional reliance on skin biopsies or blood draws. This review explores viable cell types found in urine and their potential applications.

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Area of Science:

  • Biomedical Sciences
  • Cell Biology
  • Urology

Background:

  • Traditional cell sourcing involves invasive procedures like skin biopsy or blood extraction.
  • Urine is often overlooked as a biological source due to its perception as waste.
  • Urine analysis is a established diagnostic tool with growing interest in biomarker detection.

Purpose of the Study:

  • To review the types of viable cells present in urine.
  • To highlight the potential applications of urine-derived cells in research and diagnostics.
  • To advocate for urine as a noninvasive alternative for cell collection.

Main Methods:

  • Literature review of existing research on urine cytology and cell isolation.
  • Analysis of studies demonstrating the viability and characteristics of cells in urine.
  • Synthesis of findings on the potential uses of urine-derived cells.

Main Results:

  • Urine contains a variety of viable cell types, including epithelial cells and potentially others.
  • These cells possess characteristics suitable for in vitro expansion and biological studies.
  • Recent research supports the utility of urine as a source for cellular material.

Conclusions:

  • Urine represents a promising, noninvasive source for cell collection, reducing patient discomfort.
  • The potential applications of urine-derived cells span diagnostics, regenerative medicine, and fundamental biological research.
  • Further exploration of urine as a cellular source is warranted to fully realize its benefits.