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Updated: May 18, 2026

Implementation of a Reference Interferometer for Nanodetection
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An integrated tunable interferometer controlled by liquid diffusion in polydimethylsiloxane.

Yun Zou1, Zhenhua Shen, Xiang Chen

  • 1Department of Physics, Shanghai Jiao Tong University, Shanghai 200240, China.

Optics Express
|October 6, 2012
PubMed
Summary
This summary is machine-generated.

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We developed a tunable interferometer using Polydimethylsiloxane (PDMS) fabricated with soft lithography. This microfluidic device utilizes liquid diffusion for tunable optical path differences, enabling versatile sensing applications.

Area of Science:

  • Microfluidics
  • Optical Engineering
  • Materials Science

Background:

  • On-chip interferometers typically require complex fabrication processes.
  • Developing integrated and tunable optical devices for microfluidic systems remains a challenge.

Purpose of the Study:

  • To demonstrate an integrated tunable interferometer fabricated using Polydimethylsiloxane (PDMS).
  • To leverage fluid-fluid interface diffusion for optical path difference control and tunability.
  • To provide a convenient platform for sensing applications in microfluidic networks and chemical microreactors.

Main Methods:

  • Fabrication of the interferometer using conventional soft lithography.
  • Utilizing the optical path difference generated by propagation across a fluid-fluid interface.

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  • Controlling liquid diffusion by adjusting flow rates of two miscible liquids for tunability.

    • Main Results:

    • Achieved tunability in the interferometer by controlling the diffusion level of miscible liquids.
    • Observed interference spectral shifts directly correlated with the ratio of liquid flow rates.
    • Demonstrated that interference peak numbers vary with the flow rate ratio, indicating changes in refractive index profiles.

    Conclusions:

    • The developed PDMS interferometer offers a simple, tunable, and integrated solution for microfluidic applications.
    • The device's design facilitates sensing and detection within biological systems.
    • This work paves the way for advanced sensing capabilities in chemical microreactors.