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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Pregnancy and Ehlers-Danlos vascular syndrome: patients' care and complications]
E Dubruc1, S Dupuis-Girod, P Khau Van Kien
1Service de génétique, hôpital Louis-Pradel, hospices civils de Lyon, 28, avenue Doyen-Lépine, 69500 Bron, France. estelle.dubruc@free.fr
Introduction:
Elhers-Danlos vascular syndrome type IV (EDS4) is a hereditary pathology of the connective tissue responsible for an increased risk of lethal arterial, uterine and digestive complications during and after pregnancy.
Patients And Methods:
We describe the obstetrical care, the nature and frequency of complications related to pregnancy of patients with EDS4 and their relatives.
Results:
Twenty-seven pregnancies were studied including 23 deliveries, 18 vaginal deliveries and five caesarean, no maternal death and two major life-threatening complications (8.7%) were recorded which could be directly linked to EDS4 (rupture of the biscupid valve pillar after vaginal delivery and a rupture of the caecum after a prophylactic caesarean). Ten deliveries underwent epidural anesthesia without complication. Six perineal injuries (33.3%) were observed.
Conclusion:
Pregnancy in patient with EDS4 needs obstetrical cares in a special unit's motivated medical team with intensive care and surgical disponibilities.
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