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Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Male Sexual Response: Erection & Ejaculation

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
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Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

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Penis

Penis

The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...

Infertility in Males

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

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Related Experiment Video

Updated: May 18, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Erectile dysfunction.

Rany Shamloul¹, Hussein Ghanem

¹Department of Urology, University of Ottawa, Ottawa, ON, Canada. ranyshamloul@gmail.com

Lancet (London, England)

|October 9, 2012

Summary

Erectile dysfunction (ED) affects men over 40, linked to lifestyle and cardiovascular issues. New research explores gene and cell therapies for a potential cure beyond current treatments.

Area of Science:

Urology
Cardiology
Men's Health

Background:

Erectile dysfunction (ED) is prevalent in men over 40.
Associated with diabetes, hypertension, obesity, and inactivity.
Strong predictor of cardiovascular disease, necessitating cardiac assessment.

Purpose of the Study:

To review the link between ED and cardiovascular disease.
To discuss current ED treatments and their limitations.
To explore novel therapeutic strategies for ED.

Main Methods:

Literature review of ED pathophysiology and risk factors.
Analysis of the association between ED and cardiovascular disease.
Evaluation of current and emerging ED treatments.

Related Experiment Videos

Last Updated: May 18, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Main Results:

ED is a significant indicator of coronary artery disease.
Phosphodiesterase type 5 inhibitors are effective oral therapies.
Limitations of current treatments drive research into advanced therapies.

Conclusions:

ED management requires consideration of cardiovascular health.
Gene and cell-based therapies show promise for future ED cures.
Ongoing research aims to overcome limitations of existing ED treatments.