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Aging and recurrent urinary tract infections are associated with bladder dysfunction in type 2 diabetes
Tzu-Li Lin1, Gin-Den Chen, Yi-Ching Chen
1Department of Living Sciences, National Open University, Taiwan.
Taiwanese Journal of Obstetrics & Gynecology
|October 9, 2012
Summary
Diabetic bladder dysfunction progresses over time, starting with storage issues and leading to voiding problems. Advanced age and recurrent UTIs independently worsen voiding dysfunction in diabetic women.
Area of Science:
- Urology
- Endocrinology
- Geriatrics
Background:
- Diabetes mellitus (DM) is associated with various complications, including lower urinary tract dysfunction.
- Diabetic bladder dysfunction can manifest as storage or voiding problems, impacting quality of life.
Purpose of the Study:
- To investigate the diverse urodynamic findings in women with type 2 DM.
- To evaluate the temporal progression of bladder dysfunction in diabetic women.
- To identify predisposing factors for storage and voiding dysfunction in this population.
Main Methods:
- Prospective study of 181 women with type 2 DM and lower urinary tract dysfunction.
- Complete urogynecological evaluations and urodynamic studies were performed.
- DM history, treatment, and urodynamic diagnoses were analyzed for temporal effects and predisposing factors.
Main Results:
- Bladder dysfunction showed a time-dependent progression from storage issues to impaired voiding.
- Duration of DM was longer in women with voiding dysfunction compared to those with overactive detrusor.
- Age and recurrent urinary tract infections were independent predictors of voiding dysfunction.
Conclusions:
- Urodynamic studies reveal a temporal progression in diabetic bladder dysfunction.
- Longer DM duration is linked to more severe voiding dysfunction.
- Aging and recurrent UTIs are key independent factors contributing to impaired bladder function in diabetic women.
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