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Hypertension after repair of aortic coarctation--a systematic review
Carla Canniffe1, Phalla Ou, Kevin Walsh
1Heart House, Mater Misericordiae Hospital, Dublin, Ireland; Our Lady's Children's Hospital, Dublin, Ireland. ccanniffe@hotmail.com
Insights
Hypertension is a common issue after aortic coarctation repair, affecting a significant portion of patients. Factors like surgical timing and follow-up age influence its prevalence.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Vascular Surgery
Background:
- Aortic coarctation repair is anatomically successful in many patients.
- Hypertension remains a significant concern post-repair.
Purpose of the Study:
- To determine the prevalence of hypertension after aortic coarctation repair.
- To identify factors influencing hypertension post-repair.
- To explore underlying hypotheses for hypertension in this patient group.
Main Methods:
- Systematic review of English-language articles (1987-2012) reporting systolic blood pressure (SBP) post-aortic coarctation repair.
- Searches included PubMed, Cochrane Controlled Trials Register, reference lists, and conference abstracts.
- Data extraction performed by two independent reviewers.
Main Results:
- 26 articles were included from an initial search of 12,914.
- The median prevalence of late hypertension after satisfactory aortic coarctation repair was 32.5% (range 25-68%).
Conclusions:
- Hypertension is a frequent complication following aortic coarctation repair.
- Age at surgery, age at follow-up, blood pressure measurement methods, and intervention type impact hypertension prevalence.
Unlabelled:
Hypertension continues to be a common and potentially serious problem in patients who have undergone anatomically successful repair of aortic coarctation.
Objective:
To assess the prevalence of hypertension after aortic coarctation repair, the factors that affect the prevalence and the hypotheses behind hypertension in this cohort of patients.
Design:
A systematic review of all articles reporting on systolic blood pressure (SBP) in patients who have undergone aortic coarctation repair.
Data Sources:
An electronic search of all English articles using PUBMED and The Cochrane Controlled Trials Register was performed. A manual search of references lists of relevant studies and a search of conference abstracts were also conducted.
Inclusion Criteria:
We restricted inclusion to articles published between 1987 and 2012 that reported on SBP in patients who have undergone aortic coarctation repair.
Data Extraction:
Independent extraction of articles was performed by two authors using predefined data fields. One author then proceeded to extract information of interest from these articles.
Results:
The first search yielded 12,914 articles. After screening titles, abstracts and full text articles 26 articles were included in this review article. In papers reporting the prevalence of hypertension late after anatomically satisfactory coarctation repair, the median prevalence was 32.5% (range 25-68%).
Conclusion:
Hypertension remains a common complication following aortic coarctation repair. Factors that influence the reported prevalence of hypertension include the age at the time of surgery, age at follow up, the method used to measure blood pressure and the type of intervention performed.
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