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Related Experiment Video

Updated: May 18, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Cardiac 'resynchronization' by a left lateral accessory pathway.

Antonio O Luque Lezcano¹, Jose M Porres Aracama, Francisco Garcia Urra

¹Intensive Care Medicine, Arrhythmia Unit, Hospital Donostia, Gipuzkoa (Basque Country), Spain. oskar.luke@gmail.com

Cardiology Journal

|October 9, 2012

Summary

This summary is machine-generated.

A young woman experienced tachycardia due to a left lateral pathway. Radiofrequency ablation temporarily stopped accessory pathway conduction, revealing a complete left bundle branch block.

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Area of Science:

Cardiology
Electrophysiology
Medical Case Reports

Background:

Tachycardia episodes can be caused by accessory pathways.
Pre-excitation syndromes, like Wolff-Parkinson-White syndrome, involve accessory electrical pathways between the atria and ventricles.
Left lateral pathways are a common type of accessory pathway.

Observation:

A 21-year-old woman presented with recurrent tachycardia.
Electrocardiogram (ECG) revealed a delta wave, indicative of pre-excitation via a left lateral accessory pathway.
The patient had no significant past medical history besides these episodes.

Findings:

A single radiofrequency pulse successfully terminated the accessory pathway conduction.
Following termination, the ECG demonstrated nodal conduction.
A complete left bundle branch block became apparent after the accessory pathway was ablated.

Implications:

This case highlights the diagnostic utility of electrophysiological study and ablation in identifying underlying cardiac conduction abnormalities.
Temporary ablation can unmask previously concealed conduction defects, such as bundle branch blocks.
Understanding these transient electrophysiological changes is crucial for accurate diagnosis and management of cardiac arrhythmias.