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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

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Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
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Published on: February 9, 2019

Four-dimensional structural and Doppler optical coherence tomography imaging on graphics processing units.

Marcin Sylwestrzak, Daniel Szlag, Maciej Szkulmowski

    Journal of Biomedical Optics
    |October 9, 2012
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces real-time 3-D Fourier domain optical coherence tomography (FdOCT) imaging using graphics processing unit (GPU) programming. The developed software significantly reduces data processing time for structural and Doppler OCT, enabling faster flow visualization.

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    Area of Science:

    • Biomedical Optics
    • Medical Imaging Technology
    • Computational Imaging

    Background:

    • Fourier domain optical coherence tomography (FdOCT) faces limitations due to lengthy data processing times, especially when incorporating flow visualization algorithms like Doppler analysis.
    • Previous applications of general-purpose computing on GPU (GPGPU) have focused on structural OCT imaging, but real-time 3-D flow imaging remained unaddressed.

    Discussion:

    • The developed software leverages GPGPU for accelerated processing of both structural and Doppler OCT data.
    • Optimization strategies and thread organization were implemented to achieve high-speed imaging capabilities.
    • The system demonstrates real-time visualization of 2-D data at over 120 Hz and 3-D volume imaging at approximately 9 volumes per second.

    Key Insights:

    • Achieved real-time 3-D FdOCT imaging with integrated flow visualization using GPU programming.
    • Overcame computational bottlenecks in FdOCT processing, enabling unprecedented imaging speeds.
    • Successfully visualized dynamic flow in phantoms and biological tissues, including the human eye.

    Outlook:

    • This advancement paves the way for enhanced clinical diagnostics and research applications requiring rapid, high-resolution 3-D OCT imaging.
    • Future work may involve further optimization for even higher resolutions and more complex flow analyses.
    • Potential for integration into advanced microscopy and in vivo imaging modalities.