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Glomerular lipidosis in a Syrian hamster of the APA strain
M Norimatsu1, K Doi, S Itagaki
1Department of Biomedical Science, Faculty of Agriculture, University of Tokyo, Japan.
Laboratory Animals
|January 1, 1990
Abstract:
Spontaneous glomerular lipidosis was found in a 12-week-old male Syrian hamster of the APA strain. Lipids in the glomeruli were observed as droplets in a prominently expanded mesangial area and as emboli in a dilated capillary lumen. Lipid deposition was also, but less often, detected in tubular epithelial cells and interstitial cells around the lipid-laden glomeruli. This case of glomerular lipidosis was considered to be closely related to hyperglycaemia and hyperlipidaemia.