Socket grafting with calcium phosphosilicate alloplast putty: a histomorphometric evaluation

Socket grafting with a bone graft substitute immediately after extraction is essential to preserve the ridge architecture for implant placement. Several bone graft substitutes have been tested for their ability to effectively regenerate osseous tissue in the sockets. Evidence suggests that socket bone typically regenerates during a period of 6 to 8 months or longer, depending on several factors including the original ridge dimensions, type of graft, and the overall systemic health of the individual. The purpose of this study is to histologically evaluate the bone regeneration potential of a novel synthetic calcium phosphosilicate putty (CPS) graft substitute.

After extraction of the involved teeth, CPS putty graft was placed, and the sockets were covered with a collagen plug. Cores were taken from 20 patients for histological evaluation prior to implant placement. Ten cores were processed decalcified with hematoxylin and eosin (H&E) stain and the remaining 10 were processed undecalcified. Histomorphometric data obtained from both sets is presented.

Histomorphometric analysis revealed an average vital bone content of 49.5 (± 20.7). A residual graft content of 4.3% (± 7.8) was observed following a healing time of 4.9 (± 0.8) months.

Clinical and histomorphometric data suggests that CPS putty is a good choice for socket bone regeneration in implant-related surgeries.