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Molecular adaptations to concurrent training.

E O de Souza¹, V Tricoli, H Roschel

¹Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil. desouza.eo@gmail.com

International Journal of Sports Medicine

|October 10, 2012

Summary

This summary is machine-generated.

Concurrent training (CT) effectively enhances endurance and strength, matching strength training (ST) gains in muscle size and strength. Molecular adaptations varied, but CT did not impede hypertrophy or strength development.

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Area of Science:

Exercise physiology
Molecular biology
Sports science

Background:

Concurrent training (CT) combines endurance and strength exercises.
Understanding its effects on muscle adaptations is crucial for optimizing training programs.

Purpose of the Study:

To investigate the chronic effects of CT on morphological and molecular adaptations.
To compare CT with interval training (IT) and strength training (ST).

Main Methods:

37 men participated in an 8-week training program (CT, IT, ST, or control).
Evaluated maximum strength (1RM), muscle cross-sectional area (CSA), and molecular markers (p70S6K1, Akt, AMPK).

Main Results:

CT and IT improved VO2max and time to exhaustion compared to controls.
ST and CT groups showed significant increases in 1RM and quadriceps CSA.
Molecular adaptations differed: p70S6K1 increased in CT, Akt phosphorylation in ST, and AMPK phosphorylation in IT.

Conclusions:

CT promotes significant strength and hypertrophy gains comparable to ST.
Different training modes induce distinct molecular adaptations.
CT is an effective training strategy without compromising muscle strength or size.