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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
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Factors affecting anxiety in multiple sclerosis.

A C Garfield1, N B Lincoln

  • 1Institute of Work, Health and Organisations, University of Nottingham, Nottingham, UK.

Disability and Rehabilitation
|October 11, 2012
PubMed
Summary
This summary is machine-generated.

Anxiety is prevalent in multiple sclerosis (MS). Depression significantly predicts anxiety in MS patients, alongside lower self-efficacy, higher disability, and stress.

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Psychology

Background:

  • Anxiety is a frequent comorbidity in multiple sclerosis (MS).
  • Understanding the factors contributing to anxiety in MS is crucial for effective management.
  • Limited research exists on the specific correlates of anxiety within the MS population.

Purpose of the Study:

  • To identify key factors associated with the presence of anxiety in individuals diagnosed with multiple sclerosis.
  • To investigate the relationship between anxiety and various psychological and physical health indicators in MS patients.

Main Methods:

  • A cohort study design was employed.
  • Participants completed questionnaires assessing disability, depression, self-efficacy, locus of control, general stress, psychological distress, and MS-specific factors.
  • Anxiety levels were measured using the Hospital Anxiety and Depression Scale (HADS), comparing anxious and non-anxious groups.

Main Results:

  • The study included 157 participants, with 89 (57%) exhibiting clinically significant anxiety.
  • Anxious participants demonstrated lower self-efficacy, higher disability, increased depression, and elevated stress levels (all p < 0.001).
  • Multivariate regression analysis identified depression as the sole significant predictor of anxiety (OR = 1.32, p < 0.05), explaining 46% of the variance.

Conclusions:

  • A high prevalence of anxiety was observed in the multiple sclerosis population.
  • Factors such as depression, low self-efficacy, disability, and stress are linked to an increased likelihood of experiencing anxiety in MS.
  • Depression emerged as a critical factor influencing anxiety in individuals with MS.