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The role of aspirin in post-polypectomy bleeding--a retrospective survey

Antony Pan1, Martin Schlup, Ralf Lubcke

  • 1Gastroenterology Unit, Southern District Health Board, Dunedin, New Zealand.

BMC Gastroenterology
|October 11, 2012
PubMed

Insights

Patients taking aspirin have a significantly higher risk of lower gastrointestinal bleeding after colonoscopic polypectomy. Caution is advised when performing polypectomy on patients using aspirin.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Clinical Research

Background:

  • Post-polypectomy bleeding is a common complication of colonoscopy, occurring in up to 6.1% of patients.
  • Potential risk factors for bleeding remain controversial.
  • The study specifically investigated the role of aspirin in post-polypectomy bleeding.

Purpose of the Study:

  • To determine the rate of post-polypectomy bleeding.
  • To analyze the role of potential risk factors, particularly aspirin use.

Main Methods:

  • Retrospective cohort study conducted at Dunedin Hospital, New Zealand.
  • Involved analysis of patients who underwent colonoscopic polypectomy between January 2007 and June 2009.
  • Excluded patients who had immediate surgery or presented with pre-colonoscopy bleeding symptoms.

Main Results:

  • 11 out of 493 patients (2.2%) experienced post-polypectomy bleeding within 30 days.
  • Aspirin use was significantly associated with an increased prevalence of bleeding (OR=6.72).
  • Non-steroidal anti-inflammatory drug (NSAID) use did not show a significant association with bleeding risk (OR=2.82).

Conclusions:

  • Aspirin significantly increases the risk of lower gastrointestinal bleeding after colonoscopic polypectomy.
  • Healthcare providers should exercise caution when performing polypectomy on patients taking aspirin.
  • Further research may be warranted to explore management strategies for this patient group.
Abstract

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