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Updated: May 17, 2026

Isolation and Transplantation of Different Aged Murine Thymic Grafts.
Published on: May 13, 2015
Thymoma followed by aplastic anemia - two different responses to immunosuppressive therapy
Murilo Antunes de Castro1, Mariana Antunes de Castro, Adriano de Moraes Arantes
1Faculdade de Medicina, Universidade Federal de Goiás - UFG, Goiânia, GO, Brazil.
Abstract:
Aplastic anemia is an uncommon complication of thymoma and is extremely infrequent after the surgical removal of a thymic tumor. Aplastic anemia is a result of marrow failure and is characterized by peripheral pancytopenia and severely depressed marrow cellularity; it may be an autoimmune manifestation of thymoma. As thymoma-associated hematological dyscrasias, which include pure red cell aplasia, aplastic anemia and myasthenia gravis, are supposed to be of immunologic origin, two cases of very severe aplastic anemia following the resection of lymphocytic thymomas treated with immunosuppression are herein presented.
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