Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides
Joseph T Paletta1, Maren Pink, Bridget Foley
1Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304, USA.
Organic Letters
|October 12, 2012
Abstract:
A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.
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