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Updated: May 17, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Executive function impairment in first-degree relatives of persons with schizophrenia: A meta-analysis of controlled
Kathryn G Jameson1, Henry A Nasrallah, Tracie G Northern
1Xavier University, Cincinnati, OH, United States.
Abstract:
A meta-analysis of past research evaluated the relationship between deficits in executive functioning among unaffected first-degree relatives of schizophrenia patients and healthy controls. The Wisconsin Cart Sorting Test (WCST), a reliable measurement of cognition and abstract thinking, was examined as the dependent variable. Unaffected first-degree relatives perform worse than controls on two important dimensions of the WCST. They achieve significantly less categories and significantly more perseverative errors.
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