Related Experiment Video
Updated: May 17, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Association between statin usage and prostate cancer prevention: a refined meta-analysis based on literature from the
1Department of Urology, General Hospital of Beijing Military Command, Beijing, China. hnandbjzy@gmail.com
Introduction:
Statins are cholesterol-lowering drugs that are widely used to prevent and treat atherosclerotic cardiovascular disease. It was found that statins can be associated with the occurrence of prostate cancer. However, no consensus has been concluded.
Materials And Methods:
In the present study, we provide a refined meta-analysis on the association between statins and prostate cancers. Our objective is to offer a congruent recognition of the impact of statins on prostate cancer.
Results:
Our refined analysis has included seven previous publications from the years 2005 to 2010.
Conclusions:
Based on the results, we concluded that there were associations for statin usage in preventing prostate cancer (OR 1.195, 95% CI 1.018-1.403, p = 0.029). Different from previous meta-analyses, our positive conclusion is primarily based on the recent new published literature, which supported the efficiency of statin use to control prostate cancer. More specific efforts for excluding the influence of other factors are crucial in further assessment of the efficiency of statin use.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Cancer Prevention
Some...
Atherosclerosis III: Management
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Cancer Survival Analysis