Related Experiment Video
Updated: May 17, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
[Industry-funded therapy studies: what is in the pipeline?]
P D Schellinger1, M Köhrmann, J Röther
1Neurologische Klinik und Neurogeriatrie, Johannes Wesling Klinikum Minden, Hans-Nolte-Str. 1, 32429 Minden, Deutschland. peter.schellinger@muehlenkreiskliniken.de
Abstract:
Several acute stroke trials are underway or have been recently completed. Among the latter are the ICTUS trial and the IST-3 trial. Several other approaches are being tested for thrombolytic therapy among them modern imaging-based patient selection and new thrombolytic agents, such as desmoteplase and tenecteplase. Other strategies include neuroprotection and neurorestoration, biophysical approaches, such as near infrared laser therapy, hemodynamic augmentation and sphenopalatine ganglion stimulation. Mechanical thrombectomy is practiced in many centers although randomized trials are pending and the IMS-3 trial was stopped. This overview will cover the very recently completed and currently recruiting acute ischemic stroke trials.
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