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Updated: May 17, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Acute bowel ischemia: analysis of diagnostic error by overlooked findings at MDCT angiography
Maria Cristina Firetto1, Alessandro A Lemos, Aldo Marini
1Department of Radiology, Foundation Cà Granda, IRCCS Policlinico Hospital, Via F. Sforza 35, 20122 Milan, Italy.
Abstract:
To retrospectively evaluate the frequency and type of findings that were missed in the original reports of multi-detector CT angiography (MDCTA) in patients with suspected acute bowel ischemia. From January 2007 to March 2011, a series of 35 patients who underwent MDCTA of the abdomen and pelvis and had surgery were included. The reports of the initial CT were retrospectively compared with the discharge diagnosis and surgical reports. Discrepant or missing findings were re-evaluated and divided into relevant or not relevant regarding the diagnosis. In 23 of the 35 patients (66 %), all findings were correctly diagnosed in the initial MDCTA report. In the remaining 12 of the 35 patients (34 %), lesions that were not reported were present at surgery. In 10 of the 12 (83 %) patients, the overlooked findings were relevant and subtle: gas in the portal vein (n = 3), gas in the bowel wall (n = 3), gas in the portal vein and bowel wall (n = 2), thrombotic occlusion of the superior mesenteric artery (n = 1), and thrombotic occlusion of the inferior mesenteric artery (n = 1). In 2 of the 12 (17 %) patients in whom the MDCTA-overlooked findings were classified as non-relevant, bowel ischemia was found at surgery. With retrospective image interpretation, 83 % of the patients with occlusive mesenteric ischemia at surgery were correctly identified, whereas the remaining 17 % with non-occlusive mesenteric ischemia at surgery showed non-relevant findings at MDCTA. About 33 % of relevant findings of bowel ischemia were overlooked by the initial MDCTA interpretation, most were subtle findings. However, secondary reading revealed most of these findings and can serve to improve diagnostic performance.
Insights
Subtle findings indicating acute bowel ischemia were missed in one-third of initial multi-detector CT angiography reports. A secondary review identified these overlooked signs, improving diagnostic accuracy for mesenteric ischemia.
Area of Science:
- Radiology
- Gastroenterology
- Abdominal Imaging
Background:
- Acute bowel ischemia is a surgical emergency with high morbidity and mortality.
- Multi-detector CT angiography (MDCTA) is a key imaging modality for diagnosing bowel ischemia.
- Missed or delayed diagnoses can significantly worsen patient outcomes.
Purpose of the Study:
- To determine the frequency and types of findings overlooked in initial MDCTA reports for suspected acute bowel ischemia.
- To assess the clinical relevance of these missed findings.
- To evaluate the potential for secondary review to improve diagnostic performance.
Main Methods:
- Retrospective review of 35 patients who underwent abdominal/pelvic MDCTA and subsequent surgery for suspected acute bowel ischemia.
- Comparison of initial MDCTA reports with discharge diagnoses and surgical findings.
- Classification of discrepant or missing findings as relevant or non-relevant.
Main Results:
- In 34% of patients, relevant findings were missed in the initial MDCTA report.
- Subtle findings like portal venous gas and bowel wall gas were most commonly overlooked.
- Secondary review identified most missed findings, improving diagnostic accuracy for mesenteric ischemia.
Conclusions:
- A significant proportion of relevant findings for acute bowel ischemia are missed in initial MDCTA interpretations.
- Overlooked findings are often subtle, emphasizing the need for careful review.
- Secondary interpretation of MDCTA can enhance diagnostic performance and potentially improve patient management for bowel ischemia.
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