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Updated: May 17, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)
Published on: March 7, 2017
Transcerebellar biopsy of diffuse pontine gliomas in children: a technical note
Ji Hoon Phi1, Hyun-Tai Chung, Kyu-Chang Wang
1Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, 110-744 Seoul, Republic of Korea.
Introduction:
The need for a surgical biopsy for diffuse pontine glioma (DPG) is increasing, and a safer and less invasive procedure is required.
Methods:
We describe a transcerebellar stereotactic biopsy procedure that can be safely performed in young children. Four pediatric patients with DPG underwent transcerebellar stereotactic biopsies.
Results:
All of the patients were diagnosed with gliomas, and one patient had a transient numbness of the lip margin after the procedure.
Discussion:
Transcerebellar stereotactic biopsy is a relatively safe way to obtain a tissue diagnosis for children with DPG.

