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Updated: May 17, 2026

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
Molecular characterization of artemisia virus A, a new sobemovirus isolated from Artemisia annua
Maria-Elena Ramel1, Paul Gugerli, Sébastien Besse
1Agroscope Changins-Wädenswil Research Station ACW, 1260, Nyon, Switzerland.
Abstract:
A distinct sobemovirus was isolated from diseased Artemisia annua plants grown in experimental culture plots in Switzerland. Electron microscopy performed on extracts of leaf and root samples of a diseased A. annua plant revealed icosahedral-30 nm viral particles. The complete nucleotide sequence of the viral genome was determined. The single positive-strand RNA of 4138 nt encodes four open reading frames with an organization similar to that described for sobemoviruses. Phylogenetic analysis revealed a close relationship to ryegrass mottle virus. The virus was efficiently acquired by healthy A. annua from contaminated soil samples. "Artemisia virus A" is tentatively proposed as a name for this new candidate member of the unassigned genus Sobemovirus.
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