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Micrococcus species-related peritonitis in patients receiving peritoneal dialysis
Chih-Chin Kao1, Chih-Kang Chiang, Jenq-Wen Huang
1Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan, R.O.C..
Abstract:
Peritonitis is a major complication of peritoneal dialysis (PD) and remains the most common cause of PD failure. Micrococci are catalase-positive, coagulase-negative, and gram-positive cocci that are spherical, often found in tetrad, and belong to the family Micrococcaceae. Micrococcus species are commonly found in the environment, and it is now recognized that Micrococcus species can be opportunistic pathogens in immunocompromised patients. The only consistent predisposing factor for Micrococcus infection is an immunocompromised state. We report three cases of Micrococcus PD peritonitis. Improper practice of PD may have been the causative factor. Although Micrococcus species are low-virulence pathogens, infection could result in refractory peritonitis and subsequent PD failure. Intraperitoneal administration of vancomycin for at least 2 weeks is recommended for Micrococcus peritonitis.
Insights
Micrococcus peritonitis, a complication of peritoneal dialysis (PD), can lead to PD failure. Prompt treatment with vancomycin is recommended for these infections.
Area of Science:
- Microbiology
- Nephrology
Background:
- Peritonitis is a significant complication and leading cause of failure in peritoneal dialysis (PD).
- Micrococci are gram-positive cocci, often environmental, recognized as opportunistic pathogens in immunocompromised individuals.
Observation:
- This report details three cases of Micrococcus peritonitis in patients undergoing PD.
- Improper PD practices may have contributed to the infections.
Findings:
- Micrococcus species, despite being low-virulence pathogens, can cause refractory peritonitis.
- These infections can ultimately lead to the failure of peritoneal dialysis.
Implications:
- Early recognition and treatment of Micrococcus peritonitis are crucial for PD patient outcomes.
- Intraperitoneal vancomycin for a minimum of two weeks is the recommended treatment regimen.
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