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Updated: May 17, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

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Published on: March 23, 2011

Homer-1a immediate early gene expression correlates with better cognitive performance in aging

Simon Kaja1, Nathalie Sumien, Priscilla K Borden

  • 1Department Ophthalmology and Vision Research Center, School of Medicine, University of Missouri-Kansas City, 2411 Holmes St., Kansas City, MO, 64108, USA.

Age (Dordrecht, Netherlands)
|October 12, 2012
PubMed
Summary

During aging, reduced Homer-1a/Vesl-1S protein levels correlate with cognitive and motor decline. This suggests Homer-1a/Vesl-1S may be a therapeutic target for age-related cognitive impairment.

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